((5Z)5-(1,3-benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4-one)

InChIKey	`PGPHHJBZEGSUNE-JYRVWZFOSA-N`
Compound Name	((5Z)5-(1,3-benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4-one)
Canonical SMILES	`O=C1NC(Nc2ccccc2)=N/C1=C\c1ccc2c(c1)OCO2`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	21
Pfam Stratification	Cross-Family
Avg pChEMBL	6.61
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9HAZ1	CLK4	Homo sapiens	Human	PF00069	7.6	IC50	ChEMBL
Q13627	DYRK1A	Homo sapiens	Human	PF00069	7.6	IC50	ChEMBL
P49759	CLK1	Homo sapiens	Human	PF00069	7.2	IC50	ChEMBL
Q9Y463	DYRK1B	Homo sapiens	Human	PF00069	7.2	IC50	ChEMBL
Q92630	DYRK2	Homo sapiens	Human	PF00069	7.1	IC50	ChEMBL
Q9H422	HIPK3	Homo sapiens	Human	PF00069	6.6	Kd	ChEMBL
O43781	DYRK3	Homo sapiens	Human	PF00069	6.6	IC50	ChEMBL
P21554	CNR1	Homo sapiens	Human	PF00001	6.5	IC50	ChEMBL
Q86Z02	HIPK1	Homo sapiens	Human	PF00069	6.5	Kd	ChEMBL
P49840	GSK3A	Homo sapiens	Human	PF00069	6.5	IC50	ChEMBL
P19784	CSNK2A2	Homo sapiens	Human	PF00069	6.4	IC50	ChEMBL
P67870	CSNK2B	Homo sapiens	Human	PF01214	6.4	IC50	ChEMBL
P68400	CSNK2A1	Homo sapiens	Human	PF00069	6.4	IC50	ChEMBL
Q00535	CDK5	Homo sapiens	Human	PF00069	6.4	IC50	ChEMBL
Q15078	CDK5R1	Homo sapiens	Human	PF03261	6.4	IC50	ChEMBL
P49760	CLK2	Homo sapiens	Human	PF00069	6.3	IC50	ChEMBL
Q8NEV1	CSNK2A3	Homo sapiens	Human	PF00069	6.3	IC50	ChEMBL
Q9NR20	DYRK4	Homo sapiens	Human	PF00069	6.3	IC50	ChEMBL
P49841	GSK3B	Homo sapiens	Human	PF00069	6.2	IC50	ChEMBL
P11309	PIM1	Homo sapiens	Human	PF00069	6.1	IC50	ChEMBL
P51617	IRAK1	Homo sapiens	Human	PF00531 PF00069	6.0	Kd	ChEMBL