Molecule Details
| InChIKey | PDYQEHZCPXKRDL-UHFFFAOYSA-N |
|---|---|
| Compound Name | 7-bromo-1,2,2-trimethyl-6-(1H-pyrazol-4-yl)-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one |
| Canonical SMILES | CN1c2c(sc(-c3cn[nH]c3)c2Br)C(=O)NC1(C)C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.77 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O00311 | CDC7 | Homo sapiens | Human | PF00069 | 8.0 | IC50 | ChEMBL |
| Q9UBU7 | DBF4 | Homo sapiens | Human | PF07535 | 8.0 | IC50 | ChEMBL;BindingDB |
| Q13464 | ROCK1 | Homo sapiens | Human | PF25346 PF00069 PF08912 | 7.7 | IC50 | ChEMBL;BindingDB |
| P24864 | CCNE1 | Homo sapiens | Human | PF02984 PF00134 | 7.6 | IC50 | ChEMBL |
| P24941 | CDK2 | Homo sapiens | Human | PF00069 | 7.6 | IC50 | ChEMBL;BindingDB |