Isobutyl4-(7-amino-3-(3-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenylcarbamate

InChIKey	`PDQSBODXIIIHSM-UHFFFAOYSA-N`
Compound Name	Isobutyl4-(7-amino-3-(3-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenylcarbamate
Canonical SMILES	`CC(C)COC(=O)Nc1ccc(-c2cnc3c(-c4cccc(N5CCNCC5)c4)cnn3c2N)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.95
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P06239	LCK	Homo sapiens	Human	PF07714 PF00017 PF00018	8.2	IC50	ChEMBL;BindingDB
P08631	HCK	Homo sapiens	Human	PF07714 PF00017 PF00018	6.5	IC50	ChEMBL;BindingDB
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	6.2	IC50	ChEMBL;BindingDB