Molecule Details
| InChIKey | PDMMFKSKQVNJMI-BLQWBTBKSA-N |
|---|---|
| Canonical SMILES | CCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.43 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB01420 |
|---|---|
| Drug Name | Testosterone propionate |
| CAS Number | 57-85-2 |
| Groups | approved investigational vet_approved withdrawn |
| ATC Codes | nan |
| Description | Testosterone propionate is a slower-releasing anabolic steroid with a short half-life. It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of testosterone.[T83] Testosterone propionate was developed initially by Watson labs, and FDA approved on Februar... |
Categories: Androgens Androstanes Androstenes Androstenols COMT Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Substrates Drugs that are Mainly Renally Excreted Fused-Ring Compounds Gonadal Hormones Gonadal Steroid Hormones Hormones Hormones, Hormone Substitutes, and Hormone Antagonists P-glycoprotein substrates Steroids Testosterone Congeners Testosterone and derivatives Thyroxine-binding globulin inhibitors UGT1A1 Inducers
Cross-references: BindingDB: 50215709 ChEBI: 9466 CHEMBL1170 ChemSpider: 5774 Drugs Product Database (DPD): 7488 C08158 D00959 PharmGKB: PA164751373 PubChem:5995 PubChem:46508693 RxCUI: 10382 Wikipedia: Testosterone_propionate ZINC: ZINC000000490791
Target Activities (2)
DrugBank Target Actions (8)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P02768 | ALB | Albumin | substrate | carriers |
| P04278 | SHBG | Sex hormone-binding globulin | substrate | carriers |
| P22309 | UGT1A1 | UDP-glucuronosyltransferase 1A1 | inducer | enzymes |
| P21964 | COMT | Catechol O-methyltransferase | inhibitor | enzymes |
| P08684 | CYP3A4 | Cytochrome P450 3A4 | substrate | enzymes |
| P18405 | SRD5A1 | 3-oxo-5-alpha-steroid 4-dehydrogenase | substrate | enzymes |
| P10275 | AR | Androgen receptor | agonist | targets |
| P08183 | ABCB1 | ATP-dependent translocase ABCB1 | substrate | transporters |