Molecule Details
InChIKeyPDMMFKSKQVNJMI-BLQWBTBKSA-N
Canonical SMILESCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL8.43
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB01420
Drug NameTestosterone propionate
CAS Number57-85-2
Groups approved investigational vet_approved withdrawn
ATC Codes nan
DescriptionTestosterone propionate is a slower-releasing anabolic steroid with a short half-life. It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of testosterone.[T83] Testosterone propionate was developed initially by Watson labs, and FDA approved on Februar...

Categories: Androgens Androstanes Androstenes Androstenols COMT Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Substrates Drugs that are Mainly Renally Excreted Fused-Ring Compounds Gonadal Hormones Gonadal Steroid Hormones Hormones Hormones, Hormone Substitutes, and Hormone Antagonists P-glycoprotein substrates Steroids Testosterone Congeners Testosterone and derivatives Thyroxine-binding globulin inhibitors UGT1A1 Inducers
Cross-references: BindingDB: 50215709 ChEBI: 9466 CHEMBL1170 ChemSpider: 5774 Drugs Product Database (DPD): 7488 C08158 D00959 PharmGKB: PA164751373 PubChem:5995 PubChem:46508693 RxCUI: 10382 Wikipedia: Testosterone_propionate ZINC: ZINC000000490791
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P10275 AR Homo sapiens Human PF02166 PF00104 PF00105 9.6 Ki ChEMBL;BindingDB
P05093 CYP17A1 Homo sapiens Human PF00067 7.2 IC50 ChEMBL;BindingDB
DrugBank Target Actions (8)
Target Gene Target Name Action Type
P02768 ALB Albumin substrate carriers
P04278 SHBG Sex hormone-binding globulin substrate carriers
P22309 UGT1A1 UDP-glucuronosyltransferase 1A1 inducer enzymes
P21964 COMT Catechol O-methyltransferase inhibitor enzymes
P08684 CYP3A4 Cytochrome P450 3A4 substrate enzymes
P18405 SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase substrate enzymes
P10275 AR Androgen receptor agonist targets
P08183 ABCB1 ATP-dependent translocase ABCB1 substrate transporters