Molecule Details
InChIKeyPDJVJMYVUAQPLU-KRWDZBQOSA-N
Compound NameUS11053238, Example 16b
Canonical SMILESCCN1CCN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc6n(c5c4)[C@@H](C)COC6)n3)nc2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL7.94
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P30281 CCND3 Homo sapiens Human PF02984 PF00134 8.5 IC50 ChEMBL
P11802 CDK4 Homo sapiens Human PF00069 7.9 IC50 ChEMBL;BindingDB
Q00534 CDK6 Homo sapiens Human PF00069 7.4 IC50 ChEMBL