Molecule Details
InChIKeyPDBPUXLUVDSLML-UHFFFAOYSA-N
Compound Name6-(3-Aminopropoxy)-4-[4-(1,3-benzoxazol-2-ylamino)phenyl]-2,3-dihydroisoindol-1-one
Canonical SMILESNCCCOc1cc2c(c(-c3ccc(Nc4nc5ccccc5o4)cc3)c1)CNC2=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)14
Pfam Stratification Cross-Family
Avg pChEMBL6.31
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (14)
Target Gene Organism Category Pfam pChEMBL Type Source
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.9 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.6 Ki ChEMBL
P07332 FES Homo sapiens Human PF00611 PF07714 PF00017 6.6 Ki ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.5 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.4 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.4 Ki ChEMBL
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 6.1 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.0 Ki ChEMBL
Q13555 CAMK2G Homo sapiens Human PF08332 PF00069 6.0 Ki ChEMBL
Q86V86 PIM3 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.0 Ki ChEMBL