Molecule Details
InChIKeyPCWGGOVOEWHPMG-UHFFFAOYSA-N
Compound Name2-(3-Chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine
Canonical SMILESClc1cccc(COc2cncc(N3CCNCC3)n2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Cross-Family
Avg pChEMBL6.89
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
P28335 HTR2C Homo sapiens Human PF00001 8.0 Ki ChEMBL;BindingDB
P41595 HTR2B Homo sapiens Human PF00001 8.0 Ki ChEMBL
Q99720 SIGMAR1 Homo sapiens Human PF04622 7.5 Ki ChEMBL
P46098 HTR3A Homo sapiens Human PF02931 PF02932 7.2 Ki ChEMBL
P28221 HTR1D Homo sapiens Human PF00001 7.2 Ki ChEMBL
P28223 HTR2A Homo sapiens Human PF00001 7.1 Ki ChEMBL;BindingDB
P35462 DRD3 Homo sapiens Human PF00001 6.5 Ki ChEMBL
P08912 CHRM5 Homo sapiens Human PF00001 6.5 Ki ChEMBL
P08173 CHRM4 Homo sapiens Human PF00001 6.3 Ki ChEMBL
P34969 HTR7 Homo sapiens Human PF00001 6.2 Ki ChEMBL
P20309 CHRM3 Homo sapiens Human PF00001 6.1 Ki ChEMBL
P11229 CHRM1 Homo sapiens Human PF00001 6.0 Ki ChEMBL