Molecule Details
InChIKeyPAQLCNBPWYBOJT-UHFFFAOYSA-N
Compound Name1-(3,4-difluorophenyl)-3-[4-(4-oxo-3H-quinazolin-7-yl)phenyl]urea
Canonical SMILESO=C(Nc1ccc(-c2ccc3c(=O)[nH]cnc3c2)cc1)Nc1ccc(F)c(F)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Homologous
Avg pChEMBL7.29
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 9.1 IC50 ChEMBL
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 7.0 IC50 ChEMBL
P10721 KIT Homo sapiens Human PF00047 PF07714 6.8 IC50 ChEMBL
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 6.8 IC50 ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.7 IC50 ChEMBL