Molecule Details
InChIKeyPALTUSLCLFDFQQ-MGPUTAFESA-N
Compound NameHu7691 free base
Canonical SMILESCn1nccc1-c1ccc(C(=O)N[C@@H]2CNCC[C@H]2c2ccc(F)c(F)c2)c(F)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Homologous
Avg pChEMBL6.76
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 8.4 IC50 ChEMBL;BindingDB
Q9Y243 AKT3 Homo sapiens Human PF00169 PF00069 PF00433 7.5 IC50 ChEMBL;BindingDB
P31751 AKT2 Homo sapiens Human PF00169 PF00069 PF00433 7.0 IC50 ChEMBL;BindingDB
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.6 IC50 ChEMBL;BindingDB
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.5 IC50 ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.5 IC50 ChEMBL;BindingDB
Q04759 PRKCQ Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.2 IC50 ChEMBL;BindingDB
Q15418 RPS6KA1 Homo sapiens Human PF00069 PF00433 6.1 IC50 ChEMBL;BindingDB
O00141 SGK1 Homo sapiens Human PF00069 PF00433 6.0 IC50 ChEMBL