Molecule Details
| InChIKey | PAGYYFBXLGVGOO-UHFFFAOYSA-N |
|---|---|
| Compound Name | US10214515, Example 13 |
| Canonical SMILES | Nc1c(C(=O)c2cc3ccc(Br)cc3[nH]2)cnn1-c1ccc2[nH]c(C3CC3)nc2c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.08 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P21802 | FGFR2 | Homo sapiens | Human | PF07679 PF13927 PF07714 | 8.6 | IC50 | ChEMBL;BindingDB |
| P11362 | FGFR1 | Homo sapiens | Human | PF07679 PF00047 PF07714 | 8.3 | IC50 | ChEMBL;BindingDB |
| P22607 | FGFR3 | Homo sapiens | Human | PF21165 PF07679 PF13927 PF07714 | 7.3 | IC50 | ChEMBL;BindingDB |