Molecule Details
| InChIKey | PAFKTGFSEFKSQG-PAASFTFBSA-N |
|---|---|
| Canonical SMILES | C[C@]12CC[C@H](O)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(n3cnc4ccccc43)=CC[C@@H]12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.73 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB12415 |
|---|---|
| Drug Name | Galeterone |
| CAS Number | 851983-85-2 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Galeterone has been used in trials studying the treatment of Prostate Cancer. |
Categories: Androstanes Androstenes Enzyme Inhibitors Fused-Ring Compounds Heterocyclic Compounds, Fused-Ring Steroid 17-alpha-Hydroxylase, antagonists & inhibitors Steroids
Cross-references: BindingDB: 50435990 CHEMBL2105738 ChemSpider: 9363493 PDB: TOK PubChem:11188409 PubChem:347828659 Wikipedia: Galeterone ZINC: ZINC000006718442
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P10275 | AR | Androgen receptor | inhibitor | targets |