Molecule Details
| InChIKey | PABSUYDXHABXPY-UHFFFAOYSA-N |
|---|---|
| Compound Name | Methyl 4-[4-[(2,4-dihydroxybenzoyl)-(thiophen-3-ylmethyl)amino]phenyl]quinazoline-2-carboxylate |
| Canonical SMILES | COC(=O)c1nc(-c2ccc(N(Cc3ccsc3)C(=O)c3ccc(O)cc3O)cc2)c2ccccc2n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.12 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15118 | PDK1 | Homo sapiens | Human | PF10436 PF02518 | 6.5 | IC50 | ChEMBL |
| Q15119 | PDK2 | Homo sapiens | Human | PF10436 PF02518 | 6.0 | IC50 | ChEMBL |
| Q15120 | PDK3 | Homo sapiens | Human | PF10436 PF02518 | 6.0 | IC50 | ChEMBL |
| Q16654 | PDK4 | Homo sapiens | Human | PF10436 PF02518 | 6.0 | IC50 | ChEMBL |