Molecule Details
| InChIKey | OZYUPQUCAUTOBP-QXAKKESOSA-N |
|---|---|
| Compound Name | Levallorphan |
| Canonical SMILES | C=CCN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(O)cc13 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.89 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB00504 |
|---|---|
| Drug Name | Levallorphan |
| CAS Number | 152-02-3 |
| Groups | approved |
| ATC Codes | nan |
| Description | An opioid antagonist with properties similar to those of naloxone; in addition it also possesses some agonist properties. It should be used cautiously; levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory depression such as that induced by alcohol or othe... |
Categories: Alkaloids Central Nervous System Agents Heterocyclic Compounds, Fused-Ring Morphinans Opiate Alkaloids Opioid Antagonists Peripheral Nervous System Agents Phenanthrenes Sensory System Agents
Cross-references: BindingDB: 50326673 ChEBI: 6431 CHEMBL1254682 ChemSpider: 10481920 C07069 PharmGKB: PA164749284 PubChem:5359371 PubChem:46505682 RxCUI: 6370 Therapeutic Targets Database: DAP000348 Wikipedia: Levallorphan ZINC: ZINC000003875992