InChIKey	OZVBMTJYIDMWIL-AYFBDAFISA-N
Compound Name	Bromocriptine
Canonical SMILES	CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C=C4c5cccc6[nH]c(Br)c(c56)C[C@H]4N(C)C3)(C(C)C)C(=O)N12
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	20
Pfam Stratification	Homologous
Avg pChEMBL	7.29
Source	BindingDB;ChEMBL

DrugBank ID	DB01200
Drug Name	Bromocriptine
CAS Number	25614-03-3
Groups	approved investigational withdrawn
ATC Codes	N04BC01 G02CB01
Description	Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Sy...

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Categories: Adrenergic Agonists Adrenergic Antagonists Adrenergic alpha-1 Receptor Agonists Adrenergic alpha-1 Receptor Antagonists Adrenergic alpha-2 Receptor Agonists Adrenergic alpha-Agonists Adrenergic alpha-Antagonists Agents producing tachycardia Agents that produce hypertension Alkaloids Anti-Dyskinesia Agents Anti-Parkinson Agents (Dopamine Agonist) Anti-Parkinson Drugs Antidepressive Agents Blood Glucose Lowering Agents Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Dopamine Agents Dopamine Agonists Ergolines Ergot Alkaloids and Derivatives Ergot-derivative Dopamine Receptor Agonists Ergotamines Genito Urinary System and Sex Hormones Heterocyclic Compounds, Fused-Ring Hormone Antagonists Hormones, Hormone Substitutes, and Hormone Antagonists Hypotensive Agents Nervous System Neurotransmitter Agents P-glycoprotein inhibitors P-glycoprotein substrates Prolactine Inhibitors Serotonin 5-HT2 Receptor Agonists Serotonin Agents Serotonin Modulators Serotonin Receptor Agonists

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Cross-references: BindingDB: 81993 ChEBI: 3181 CHEMBL493 ChemSpider: 28858 Drugs Product Database (DPD): 11220 C06856 D03165 PDB: 08Y PharmGKB: PA448671 PubChem:31101 PubChem:46505504 RxCUI: 1760 Therapeutic Targets Database: DAP001462 Wikipedia: Bromocriptine ZINC: ZINC000053683151