Molecule Details
InChIKeyOZFFKOSQNBBYCA-UHFFFAOYSA-N
Compound NameN-(5-(3,5-dicyano-1,2,6-trimethyl-1,4-dihydropyridin-4-yl)-6-fluoro-7-methyl-1H-indazol-3-yl)-2-ethylbenzamide
Canonical SMILESCCc1ccccc1C(=O)Nc1n[nH]c2c(C)c(F)c(C3C(C#N)=C(C)N(C)C(C)=C3C#N)cc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Cross-Family
Avg pChEMBL7.25
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
P54646 PRKAA2 Homo sapiens Human PF16579 PF21147 PF00069 8.2 IC50 ChEMBL
Q15418 RPS6KA1 Homo sapiens Human PF00069 PF00433 8.0 IC50 ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 8.0 IC50 ChEMBL
Q15349 RPS6KA2 Homo sapiens Human PF00069 PF00433 7.6 IC50 ChEMBL
Q9UK32 RPS6KA6 Homo sapiens Human PF00069 PF00433 7.4 IC50 ChEMBL
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 7.4 IC50 ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 7.3 IC50 ChEMBL
Q9Y6E0 STK24 Homo sapiens Human PF20929 PF00069 7.0 IC50 ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.9 IC50 ChEMBL
P80404 ABAT Homo sapiens Human PF00202 6.7 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.3 IC50 ChEMBL
P21728 DRD1 Homo sapiens Human PF00001 6.2 Ki ChEMBL