Molecule Details
InChIKeyOZBMIGDQBBMIRA-CQSZACIVSA-N
Compound NameN-(3-chloro-2-pyridinyl)-N-[(3R)-piperidin-3-yl]-5-(triazolo[4,5-b]pyridin-3-yl)pyridine-2-carboxamide
Canonical SMILESO=C(c1ccc(-n2nnc3cccnc32)cn1)N(c1ncccc1Cl)[C@@H]1CCCNC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)78
Pfam Stratification Cross-Family
Avg pChEMBL6.15
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (78)
Target Gene Organism Category Pfam pChEMBL Type Source
P05386 RPLP1 Homo sapiens Human PF00428 6.2 IC50 ChEMBL
P05388 RPLP0 Homo sapiens Human PF00428 PF00466 PF17777 6.2 IC50 ChEMBL
P08708 RPS17 Homo sapiens Human PF00833 6.2 IC50 ChEMBL
P08865 RPSA Homo sapiens Human PF16122 PF00318 6.2 IC50 ChEMBL
P15880 RPS2 Homo sapiens Human PF00333 PF03719 6.2 IC50 ChEMBL
P18077 RPL35A Homo sapiens Human PF01247 6.2 IC50 ChEMBL
P18124 RPL7 Homo sapiens Human PF00327 PF08079 6.2 IC50 ChEMBL
P18621 RPL17 Homo sapiens Human PF00237 6.2 IC50 ChEMBL
P22090 RPS4Y1 Homo sapiens Human PF16121 PF00467 PF00900 PF08071 6.2 IC50 ChEMBL
P23396 RPS3 Homo sapiens Human PF07650 PF00189 6.2 IC50 ChEMBL
P25398 RPS12 Homo sapiens Human PF01248 6.2 IC50 ChEMBL
P26373 RPL13 Homo sapiens Human PF01294 6.2 IC50 ChEMBL
P27635 RPL10 Homo sapiens Human PF00252 6.2 IC50 ChEMBL
P30050 RPL12 Homo sapiens Human PF00298 PF03946 6.2 IC50 ChEMBL
P32969 RPL9 Homo sapiens Human PF00347 6.2 IC50 ChEMBL
P35268 RPL22 Homo sapiens Human PF01776 6.2 IC50 ChEMBL
P36578 RPL4 Homo sapiens Human PF14374 PF00573 6.2 IC50 ChEMBL
P39019 RPS19 Homo sapiens Human PF01090 6.2 IC50 ChEMBL
P39023 RPL3 Homo sapiens Human PF00297 6.2 IC50 ChEMBL
P40429 RPL13A Homo sapiens Human PF00572 6.2 IC50 ChEMBL
P42677 RPS27 Homo sapiens Human PF01667 6.2 IC50 ChEMBL
P42766 RPL35 Homo sapiens Human PF00831 6.2 IC50 ChEMBL
P46776 RPL27A Homo sapiens Human PF00828 6.2 IC50 ChEMBL
P46777 RPL5 Homo sapiens Human PF14204 PF17144 6.2 IC50 ChEMBL
P46778 RPL21 Homo sapiens Human PF01157 6.2 IC50 ChEMBL
P46779 RPL28 Homo sapiens Human PF01778 6.2 IC50 ChEMBL
P46781 RPS9 Homo sapiens Human PF00163 PF01479 6.2 IC50 ChEMBL
P46782 RPS5 Homo sapiens Human PF00177 6.2 IC50 ChEMBL
P46783 RPS10 Homo sapiens Human PF03501 6.2 IC50 ChEMBL
P47914 RPL29 Homo sapiens Human PF01779 6.2 IC50 ChEMBL
P49207 RPL34 Homo sapiens Human PF01199 6.2 IC50 ChEMBL
P50914 RPL14 Homo sapiens Human PF01929 6.2 IC50 ChEMBL
P60866 RPS20 Homo sapiens Human PF00338 6.2 IC50 ChEMBL
P61247 RPS3A Homo sapiens Human PF01015 6.2 IC50 ChEMBL
P61254 RPL26 Homo sapiens Human PF00467 PF16906 6.2 IC50 ChEMBL
P61313 RPL15 Homo sapiens Human PF00827 6.2 IC50 ChEMBL
P61353 RPL27 Homo sapiens Human PF00467 PF01777 6.2 IC50 ChEMBL
P61513 RPL37A Homo sapiens Human PF01780 6.2 IC50 ChEMBL
P61927 RPL37 Homo sapiens Human PF01907 6.2 IC50 ChEMBL
P62081 RPS7 Homo sapiens Human PF01251 6.2 IC50 ChEMBL
P62241 RPS8 Homo sapiens Human PF01201 6.2 IC50 ChEMBL
P62244 RPS15A Homo sapiens Human PF00410 6.2 IC50 ChEMBL
P62249 RPS16 Homo sapiens Human PF00380 6.2 IC50 ChEMBL
P62263 RPS14 Homo sapiens Human PF00411 6.2 IC50 ChEMBL
P62266 RPS23 Homo sapiens Human PF00164 6.2 IC50 ChEMBL
P62269 RPS18 Homo sapiens Human PF00416 6.2 IC50 ChEMBL
P62273 RPS29 Homo sapiens Human PF00253 6.2 IC50 ChEMBL
P62277 RPS13 Homo sapiens Human PF08069 PF00312 6.2 IC50 ChEMBL
P62280 RPS11 Homo sapiens Human PF00366 PF16205 6.2 IC50 ChEMBL
P62424 RPL7A Homo sapiens Human PF01248 6.2 IC50 ChEMBL
P62701 RPS4X Homo sapiens Human PF16121 PF00467 PF00900 PF08071 6.2 IC50 ChEMBL
P62750 RPL23A Homo sapiens Human PF00276 PF03939 6.2 IC50 ChEMBL
P62753 RPS6 Homo sapiens Human PF01092 6.2 IC50 ChEMBL
P62829 RPL23 Homo sapiens Human PF00238 6.2 IC50 ChEMBL
P62841 RPS15 Homo sapiens Human PF00203 6.2 IC50 ChEMBL
P62847 RPS24 Homo sapiens Human PF01282 6.2 IC50 ChEMBL
P62851 RPS25 Homo sapiens Human PF03297 6.2 IC50 ChEMBL
P62854 RPS26 Homo sapiens Human PF01283 6.2 IC50 ChEMBL
P62857 RPS28 Homo sapiens Human PF01200 6.2 IC50 ChEMBL
P62861 FAU Homo sapiens Human PF04758 PF00240 6.2 IC50 ChEMBL
P62888 RPL30 Homo sapiens Human PF01248 6.2 IC50 ChEMBL
P62891 RPL39 Homo sapiens Human PF00832 6.2 IC50 ChEMBL
P62899 RPL31 Homo sapiens Human PF01198 6.2 IC50 ChEMBL
P62906 RPL10A Homo sapiens Human PF00687 6.2 IC50 ChEMBL
P62910 RPL32 Homo sapiens Human PF01655 6.2 IC50 ChEMBL
P62913 RPL11 Homo sapiens Human PF00281 PF00673 6.2 IC50 ChEMBL
P62917 RPL8 Homo sapiens Human PF03947 PF00181 6.2 IC50 ChEMBL
P62945 RPL41 Homo sapiens Human PF05162 6.2 IC50 ChEMBL
P62979 RPS27A Homo sapiens Human PF01599 PF00240 6.2 IC50 ChEMBL
P63173 RPL38 Homo sapiens Human PF01781 6.2 IC50 ChEMBL
P63220 RPS21 Homo sapiens Human PF01249 6.2 IC50 ChEMBL
P83731 RPL24 Homo sapiens Human PF01246 6.2 IC50 ChEMBL
P83881 RPL36A Homo sapiens Human PF00935 6.2 IC50 ChEMBL
P84098 RPL19 Homo sapiens Human PF01280 PF25476 6.2 IC50 ChEMBL
Q02543 RPL18A Homo sapiens Human PF01775 6.2 IC50 ChEMBL
Q02878 RPL6 Homo sapiens Human PF01159 PF03868 6.2 IC50 ChEMBL
Q07020 RPL18 Homo sapiens Human PF17135 6.2 IC50 ChEMBL
Q9Y3U8 RPL36 Homo sapiens Human PF01158 6.2 IC50 ChEMBL