Molecule Details
InChIKeyOYWNKAAPXTYEBN-UHFFFAOYSA-N
Compound NameNvp-cee321
Canonical SMILESCc1cccc(Nc2cc(Nc3ccccc3Cl)c(C(N)=O)cn2)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL7.07
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 7.3 IC50 ChEMBL
P23458 JAK1 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 7.3 IC50 ChEMBL
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 7.2 IC50 ChEMBL
P29597 TYK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 7.2 IC50 ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 7.0 IC50 ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.4 IC50 ChEMBL