Molecule Details
| InChIKey | OYHQOLUKZRVURQ-HZJYTTRNSA-N |
|---|---|
| Compound Name | Linoleic Acid |
| Canonical SMILES | CCCCC/C=C\C/C=C\CCCCCCCC(=O)O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.62 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB14104 |
|---|---|
| Drug Name | Linoleic acid |
| CAS Number | 60-33-3 |
| Groups | approved |
| ATC Codes | nan |
| Description | nan |
Categories: Fatty Acids Fatty Acids, Essential Fatty Acids, Omega-6 Fatty Acids, Unsaturated Linoleic Acids Lipids
Cross-references: BindingDB: 22231 ChEBI: 17351 CHEMBL267476 ChemSpider: 4444105 Drugs Product Database (DPD): 10221 C01595 PDB: EIC RxCUI: 6400 Wikipedia: Linoleic_acid ZINC: ZINC000004474613
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q07869 | PPARA | Homo sapiens | Human | PF00104 PF00105 | 8.3 | Kd | ChEMBL;BindingDB |
| P42330 | AKR1C3 | Homo sapiens | Human | PF00248 | 6.2 | IC50 | ChEMBL;BindingDB |
| P05413 | FABP3 | Homo sapiens | Human | PF00061 | 6.0 | IC50 | ChEMBL;BindingDB |
| P15090 | FABP4 | Homo sapiens | Human | PF00061 | 6.0 | IC50 | ChEMBL;BindingDB |
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P15090 | FABP4 | Fatty acid-binding protein, adipocyte | inhibitor | targets |