Molecule Details
| InChIKey | OWWOVESWHWBLEI-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-(2-fluoroethyl)-1-[(6-methoxy-5-methyl-pyrimidin-4-yl)methyl]-6-methyl-pyrrolo[3,2-b]pyridine-3-carboxamide |
| Canonical SMILES | COc1ncnc(Cn2cc(C(=O)NCCF)c3ncc(C)cc32)c1C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.0 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O43924 | PDE6D | Homo sapiens | Human | PF05351 | 6.0 | IC50 | ChEMBL |
| P16499 | PDE6A | Homo sapiens | Human | PF01590 PF00233 | 6.0 | IC50 | ChEMBL |
| P18545 | PDE6G | Homo sapiens | Human | PF04868 | 6.0 | IC50 | ChEMBL |
| P35913 | PDE6B | Homo sapiens | Human | PF01590 PF00233 | 6.0 | IC50 | ChEMBL |
| P51160 | PDE6C | Homo sapiens | Human | PF01590 PF00233 | 6.0 | IC50 | ChEMBL |
| Q13956 | PDE6H | Homo sapiens | Human | PF04868 | 6.0 | IC50 | ChEMBL |