Molecule Details
InChIKeyOWBQCPZBRPKYKE-UHFFFAOYSA-N
Compound Name(4-Amino-2-((4-methoxyphenyl)amino)thiazol-5-yl)(3,4-dimethoxyphenyl)methanone
Canonical SMILESCOc1ccc(Nc2nc(N)c(C(=O)c3ccc(OC)c(OC)c3)s2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Cross-Family
Avg pChEMBL7.54
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
A6NNZ2 TUBB8B Homo sapiens Human PF00091 PF03953 7.6 IC50 ChEMBL
P04350 TUBB4A Homo sapiens Human PF00091 PF03953 7.6 IC50 ChEMBL
P07437 TUBB Homo sapiens Human PF00091 PF03953 7.6 IC50 ChEMBL
P68371 TUBB4B Homo sapiens Human PF00091 PF03953 7.6 IC50 ChEMBL
Q13509 TUBB3 Homo sapiens Human PF00091 PF03953 7.6 IC50 ChEMBL;BindingDB
Q13885 TUBB2A Homo sapiens Human PF00091 PF03953 7.6 IC50 ChEMBL
Q3ZCM7 TUBB8 Homo sapiens Human PF00091 PF03953 7.6 IC50 ChEMBL
Q9BUF5 TUBB6 Homo sapiens Human PF00091 PF03953 7.6 IC50 ChEMBL
Q9BVA1 TUBB2B Homo sapiens Human PF00091 PF03953 7.6 IC50 ChEMBL
Q9H4B7 TUBB1 Homo sapiens Human PF00091 PF03953 7.6 IC50 ChEMBL
Q9NRA0 SPHK2 Homo sapiens Human PF00781 PF19279 7.2 IC50 ChEMBL;BindingDB
Q9NYA1 SPHK1 Homo sapiens Human PF00781 7.2 IC50 ChEMBL;BindingDB