Molecule Details
| InChIKey | OVFRNPXWYQUNHR-UHFFFAOYSA-N |
|---|---|
| Compound Name | Tert-butyl 7-chloro-4-methyl-5-oxo-4,5-dihydroimidazo[1,5-a]quinazoline-3-carboxylate |
| Canonical SMILES | Cn1c(=O)c2cc(Cl)ccc2n2cnc(C(=O)OC(C)(C)C)c12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.12 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P31644 | GABRA5 | Homo sapiens | Human | PF02931 PF02932 | 9.2 | Ki | ChEMBL;BindingDB |
| P14867 | GABRA1 | Homo sapiens | Human | PF02931 PF02932 | 7.8 | Ki | ChEMBL;BindingDB |
| P18507 | GABRG2 | Homo sapiens | Human | PF02931 PF02932 | 7.8 | Ki | ChEMBL |
| P28472 | GABRB3 | Homo sapiens | Human | PF02931 PF02932 | 7.8 | Ki | ChEMBL |