Molecule Details
InChIKeyOVDBDNFZYMESOZ-JLHYYAGUSA-N
Compound NameN-(1,3-benzodioxol-5-yl)-2-[(E)-2-(2-methoxyphenyl)ethenyl]quinazolin-4-amine
Canonical SMILESCOc1ccccc1/C=C/c1nc(Nc2ccc3c(c2)OCO3)c2ccccc2n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Homologous
Avg pChEMBL6.51
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.7 IC50 ChEMBL;BindingDB
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.7 IC50 ChEMBL;BindingDB
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 6.7 IC50 ChEMBL;BindingDB
Q06187 BTK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 6.6 IC50 ChEMBL;BindingDB
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 6.3 IC50 ChEMBL;BindingDB
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 6.3 IC50 ChEMBL;BindingDB
P41240 CSK Homo sapiens Human PF07714 PF00017 PF00018 6.2 IC50 ChEMBL;BindingDB