Molecule Details
InChIKeyOSJJYEUEJRVVOD-UHFFFAOYSA-N
Compound NamePipamazine
Canonical SMILESNC(=O)C1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)17
Pfam Stratification Cross-Family
Avg pChEMBL7.85
SourceChEMBL;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB20091
Drug NamePipamazine
CAS Number84-04-8
Groups experimental
ATC Codes nan
DescriptionPipamazine is a small molecule drug. Pipamazine has a monoisotopic molecular weight of 401.13 Da.

Cross-references: ChEBI: 135641 CHEMBL1909072 ZINC: ZINC000000538183
Target Activities (17)
Target Gene Organism Category Pfam pChEMBL Type Source
P35348 ADRA1A Homo sapiens Human PF00001 9.0 pIC50 TTD_MultiTarget
P28223 HTR2A Homo sapiens Human PF00001 9.0 IC50 ChEMBL
P18089 ADRA2B Homo sapiens Human PF00001 8.9 IC50 ChEMBL
P25100 ADRA1D Homo sapiens Human PF00001 8.9 IC50 ChEMBL
P14416 DRD2 Homo sapiens Human PF00001 8.6 IC50 ChEMBL
P35462 DRD3 Homo sapiens Human PF00001 8.6 IC50 ChEMBL
P35367 HRH1 Homo sapiens Human PF00001 8.5 IC50 ChEMBL
P28335 HTR2C Homo sapiens Human PF00001 7.8 IC50 ChEMBL
P18825 ADRA2C Homo sapiens Human PF00001 7.8 IC50 ChEMBL
P21728 DRD1 Homo sapiens Human PF00001 7.7 IC50 ChEMBL
P41595 HTR2B Homo sapiens Human PF00001 7.4 IC50 ChEMBL
P08913 ADRA2A Homo sapiens Human PF00001 7.4 IC50 ChEMBL
Q99720 SIGMAR1 Homo sapiens Human PF04622 7.1 IC50 ChEMBL
P50406 HTR6 Homo sapiens Human PF00001 7.1 IC50 ChEMBL
P10635 CYP2D6 Homo sapiens Human PF00067 7.0 IC50 ChEMBL
P23975 SLC6A2 Homo sapiens Human PF00209 6.3 IC50 ChEMBL
P31645 SLC6A4 Homo sapiens Human PF03491 PF00209 6.3 IC50 ChEMBL