Molecule Details
InChIKeyOQLKNTOKMBVBKV-UHFFFAOYSA-N
Canonical SMILESN=C(N)c1ccc(OCCCCCCOc2ccc(C(=N)N)cc2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.34
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB03808
Drug NameHexamidine
CAS Number3811-75-4
Groups approved investigational
ATC Codes S03AA05 D08AC04 R02AA18 R01AX07 S01AX08
Descriptionnan

Categories: Amidines Anti-Infective Agents Anti-Infective Agents, Local Antiseptics and Disinfectants Biguanides and Amidines Dermatologicals Nasal Preparations Ophthalmological and Otological Preparations Ophthalmologicals Sensory Organs Throat Preparations
Cross-references: BindingDB: 50015234 ChEBI: 87184 CHEMBL25105 ChemSpider: 58639 Drugs Product Database (DPD): 4164 PDB: DID PubChem:65130 PubChem:46505102 RxCUI: 26849 Wikipedia: Hexamidine ZINC: ZINC000001705403
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P00734 F2 Homo sapiens Human PF00594 PF00051 PF09396 PF00089 6.7 Ki ChEMBL;BindingDB
Q9Y5Y6 ST14 Homo sapiens Human PF00431 PF00057 PF01390 PF00089 6.0 Ki ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P0A0N4 P0A0N4 HTH-type transcriptional regulator QacR binder targets
P0A0N5 P0A0N5 HTH-type transcriptional regulator QacR binder targets