Molecule Details
| InChIKey | OQCIHSFMLURANM-YFKPBYRVSA-N |
|---|---|
| Compound Name | {(S)-1-[(7-Iodo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-amino]-ethyl}-phosphonic acid |
| Canonical SMILES | C[C@@H](NCc1cc(I)cc2nc(O)c(O)nc12)P(=O)(O)O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.8 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q05586 | GRIN1 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 8.1 | IC50 | ChEMBL;BindingDB |
| P42261 | GRIA1 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.5 | IC50 | ChEMBL |
| P42262 | GRIA2 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.5 | IC50 | ChEMBL |
| P42263 | GRIA3 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.5 | IC50 | ChEMBL |
| P48058 | GRIA4 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.5 | IC50 | ChEMBL |