4-(4-chlorophenyl)-1-cyclopropyl-5-(3,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-3-(hydroxymethyl)-4,5-dihydropyrrolo-[3,4-c]pyrazol-6(1H)-one

InChIKey	`OQBRSKHYDQIBJE-UHFFFAOYSA-N`
Compound Name	4-(4-chlorophenyl)-1-cyclopropyl-5-(3,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-3-(hydroxymethyl)-4,5-dihydropyrrolo-[3,4-c]pyrazol-6(1H)-one
Canonical SMILES	`Cc1cc(N2C(=O)c3c(c(CO)nn3C3CC3)C2c2ccc(Cl)cc2)cn2c(C)nnc12`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.35
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O60885	BRD4	Homo sapiens	Human	PF17035 PF17105 PF00439	7.4	IC50	ChEMBL;BindingDB
P25440	BRD2	Homo sapiens	Human	PF17035 PF00439	7.3	IC50	ChEMBL;BindingDB
Q15059	BRD3	Homo sapiens	Human	PF17035 PF00439	7.3	IC50	ChEMBL;BindingDB