Molecule Details
InChIKeyOPLHMHMCXQXEQG-UHFFFAOYSA-N
Compound Name3-(2-aminoethylsulfamoyl)-N-[4-(4-oxo-3H-phthalazin-1-yl)phenyl]benzamide
Canonical SMILESNCCNS(=O)(=O)c1cccc(C(=O)Nc2ccc(-c3n[nH]c(=O)c4ccccc34)cc2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL6.48
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.8 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 7.1 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.0 Ki ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 6.3 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.1 Ki ChEMBL
Q96SB4 SRPK1 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.0 Ki ChEMBL
P42685 FRK Homo sapiens Human PF07714 PF00017 PF00018 6.0 Ki ChEMBL