Molecule Details
InChIKeyOPHYHBRVLAQKEG-MHZLTWQESA-N
Compound Name(2S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluorophenyl)-4-spiro[indene-1,4'-piperidine]-1'-ylbutanamide
Canonical SMILESO=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@@H](CCN1CCC2(C=Cc3ccccc32)CC1)c1ccc(F)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.31
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P51681 CCR5 Homo sapiens Human PF00001 7.5 IC50 ChEMBL;BindingDB
P25103 TACR1 Homo sapiens Human PF00001 7.3 IC50 ChEMBL;BindingDB
P41597 CCR2 Homo sapiens Human PF00001 7.1 IC50 ChEMBL;BindingDB