Molecule Details
InChIKeyOPFUTVRZTCWTRC-UHFFFAOYSA-N
Compound Name1-[3-(2,2-Difluorocyclopropyl)-1-phenylpyrazol-5-yl]-3-(4-fluoro-3-methylphenyl)urea
Canonical SMILESCc1cc(NC(=O)Nc2cc(C3CC3(F)F)nn2-c2ccccc2)ccc1F
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL6.29
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P48544 KCNJ5 Homo sapiens Human PF01007 PF17655 6.7 IC50 ChEMBL;BindingDB
P48051 KCNJ6 Homo sapiens Human PF01007 PF17655 6.1 IC50 ChEMBL
P48549 KCNJ3 Homo sapiens Human PF01007 PF17655 6.1 IC50 ChEMBL;BindingDB