Molecule Details
| InChIKey | ONSBFNASIDWXPA-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6-carbamimidoyl-N-(3-cyclopentyloxyphenyl)-4-(5-ethylsulfonylfuran-3-yl)naphthalene-2-carboxamide |
| Canonical SMILES | CCS(=O)(=O)c1cc(-c2cc(C(=O)Nc3cccc(OC4CCCC4)c3)cc3ccc(C(=N)N)cc23)co1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.6 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00749 | PLAU | Homo sapiens | Human | PF00051 PF00089 | 8.7 | Ki | ChEMBL;BindingDB |
| P07477 | PRSS1 | Homo sapiens | Human | PF00089 | 8.5 | Ki | ChEMBL;BindingDB |
| P00747 | PLG | Homo sapiens | Human | PF00051 PF00024 PF00089 | 7.4 | Ki | ChEMBL;BindingDB |
| P06870 | KLK1 | Homo sapiens | Human | PF00089 | 7.2 | Ki | ChEMBL;BindingDB |
| P00734 | F2 | Homo sapiens | Human | PF00594 PF00051 PF09396 PF00089 | 6.2 | Ki | ChEMBL;BindingDB |