Molecule Details
| InChIKey | OLFHSOXJKHUDGA-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1,3-Dihydroisoindol-2-yl-(2,4-dihydroxy-5-indol-1-ylphenyl)methanone |
| Canonical SMILES | O=C(c1cc(-n2ccc3ccccc32)c(O)cc1O)N1Cc2ccccc2C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.66 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P07900 | HSP90AA1 | Homo sapiens | Human | PF13589 PF00183 | 7.4 | IC50 | ChEMBL;BindingDB |
| P14625 | HSP90B1 | Homo sapiens | Human | PF13589 PF00183 | 6.5 | Kd | ChEMBL |
| Q12931 | TRAP1 | Homo sapiens | Human | PF13589 PF00183 | 6.4 | Kd | ChEMBL |
| P08238 | HSP90AB1 | Homo sapiens | Human | PF13589 PF00183 | 6.3 | Kd | ChEMBL |