1-(4-sulfamoylphenyl)-3-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl}thiourea

InChIKey	`OKQRJNSDZLFCKE-CUYVQJCZSA-N`
Compound Name	1-(4-sulfamoylphenyl)-3-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl}thiourea
Canonical SMILES	`CC1(C)O[C@@H]2[C@@H](CO[C@@]3(CNC(=S)Nc4ccc(S(N)(=O)=O)cc4)OC(C)(C)O[C@@H]23)O1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	7.38
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P22748	CA4	Homo sapiens	Human	PF00194	8.0	Ki	ChEMBL;BindingDB
P43166	CA7	Homo sapiens	Human	PF00194	7.4	Ki	ChEMBL;BindingDB
P00918	CA2	Homo sapiens	Human	PF00194	7.2	Ki	ChEMBL;BindingDB
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	7.2	pIC50	TTD_MultiTarget
Q16790	CA9	Homo sapiens	Human	PF00194	7.1	Ki	ChEMBL;BindingDB