Molecule Details
| InChIKey | OKLYWXAJDGCACQ-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-(4-fluorobenzyl)-5,6-dihydroxy-2-thien-2-ylpyrimidine-4-carboxamide |
| Canonical SMILES | O=C(NCc1ccc(F)cc1)c1nc(-c2cccs2)[nH]c(=O)c1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.54 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P04585 | gag-pol | Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) | Pathogen | PF00540 PF19317 PF00552 PF02022 PF00075 PF00665 PF00077 PF00078 PF06815 PF06817 PF00098 | 8.0 | IC50 | BindingDB |
| Q76353 | Human immunodeficiency virus type 1 | Pathogen | PF00552 PF02022 PF00665 | 8.0 | IC50 | BindingDB | |
| Q7ZJM1 | pol | Human immunodeficiency virus type 1 | Pathogen | PF00552 PF02022 PF00665 | 8.0 | IC50 | ChEMBL |
| P16732 | TRM3 | Human cytomegalovirus (strain AD169) | Pathogen | PF02499 PF02500 | 6.2 | IC50 | ChEMBL |