Molecule Details
| InChIKey | OKHAMDQBTFJMMY-UHFFFAOYSA-N |
|---|---|
| Compound Name | [8-methoxy-4-propan-2-yl-1-[3-(1H-pyrazol-4-yl)quinolin-6-yl]-3,5-dihydro-2H-1,4-benzodiazepin-6-yl]methanol |
| Canonical SMILES | COc1cc(CO)c2c(c1)N(c1ccc3ncc(-c4cn[nH]c4)cc3c1)CCN(C(C)C)C2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.27 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P11362 | FGFR1 | Homo sapiens | Human | PF07679 PF00047 PF07714 | 6.5 | Kd | ChEMBL;BindingDB |
| P22607 | FGFR3 | Homo sapiens | Human | PF21165 PF07679 PF13927 PF07714 | 6.3 | Kd | ChEMBL;BindingDB |
| P21802 | FGFR2 | Homo sapiens | Human | PF07679 PF13927 PF07714 | 6.0 | Kd | ChEMBL;BindingDB |