3-[4-[[2-[1-(4-Tert-butyl-2-chloro-phenyl)tetrazol-5-yl]sulfanylacetyl]amino]-3-chloro-phenyl]prop-2-ynoic acid

InChIKey	`OKDKQGCRSIBHSQ-UHFFFAOYSA-N`
Compound Name	3-[4-[[2-[1-(4-Tert-butyl-2-chloro-phenyl)tetrazol-5-yl]sulfanylacetyl]amino]-3-chloro-phenyl]prop-2-ynoic acid
Canonical SMILES	`CC(C)(C)c1ccc(-n2nnnc2SCC(=O)Nc2ccc(C#CC(=O)O)cc2Cl)c(Cl)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.26
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9WKE8	reverse transcriptase	Human immunodeficiency virus type 1	Pathogen	PF00078	8.5	IC50	BindingDB
Q72547	pol	Human immunodeficiency virus type 1	Pathogen	PF00075 PF00078 PF06815 PF06817	8.0	IC50	ChEMBL