InChIKey	OIGNJSKKLXVSLS-VWUMJDOOSA-N
Compound Name	Prednisolone
Canonical SMILES	C[C@]12C=CC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)CO
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	7
Pfam Stratification	Cross-Family
Avg pChEMBL	7.5
Source	ChEMBL;BindingDB

DrugBank ID	DB00860
Drug Name	Prednisolone
CAS Number	50-24-8
Groups	approved investigational vet_approved
ATC Codes	D07AA03 S01CA02 D07XA02 A01AC54 R01AD02 S01BB02 S01CB02 R01AD52 V03AB05 S03BA02 D07BA01 D07CA03 S01BA04 S02BA03 A01AC04 A07EA01 H02AB06 S02CA01 C05AA04 S03CA02
Description	Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.[A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]

---

Categories: Adrenal Cortex Hormones Adrenals Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use Alimentary Tract and Metabolism Anti-Inflammatory Agents Antidiarrheals, Intestinal Antiinflammatory/antiinfective Agents Antidotes Antineoplastic Agents Antineoplastic Agents, Hormonal Antineoplastic and Immunomodulating Agents Corticosteroid Hormone Receptor Agonists Corticosteroids Corticosteroids Acting Locally Corticosteroids for Local Oral Treatment Corticosteroids for Systemic Use Corticosteroids for Systemic Use, Plain Corticosteroids, Dermatological Preparations Corticosteroids, Weak (Group I) Cytochrome P-450 CYP3A Inducers Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inducers Cytochrome P-450 CYP3A4 Inducers (strength unknown) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Substrates Dermatologicals Endocrine Therapy Fused-Ring Compounds Hormone Antagonists and Related Agents Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Hyperglycemia-Associated Agents Immunosuppressive Agents Intestinal Antiinflammatory Agents Nasal Preparations Ophthalmological and Otological Preparations Ophthalmologicals Otologicals P-glycoprotein substrates Prednisolone and Prodrugs Pregnadienes Pregnadienetriols Pregnanes Sensory Organs Steroids Stomatological Preparations Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins Vasoprotectives

---

Cross-references: BindingDB: 19190 ChEBI: 8378 CHEMBL131 ChemSpider: 5552 Drugs Product Database (DPD): 7617 Guide to Pharmacology: 2866 IUPHAR: 2866 C07369 D00472 PDB: TUA PharmGKB: PA451096 PubChem:5755 PubChem:46504847 RxCUI: 8638 Therapeutic Targets Database: DAP000419 Wikipedia: Prednisolone ZINC: ZINC000003833821