InChIKey	OGJPXUAPXNRGGI-UHFFFAOYSA-N
Compound Name	Norfloxacin
Canonical SMILES	CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.15
Source	ChEMBL;BindingDB

DrugBank ID	DB01059
Drug Name	Norfloxacin
CAS Number	70458-96-7
Groups	approved investigational
ATC Codes	J01RA14 J01RA13 S01AE02 J01MA06
Description	A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.

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Categories: 4-Quinolones Agents Causing Muscle Toxicity Anti-Bacterial Agents Anti-Infective Agents Antibacterials for Systemic Use Antiinfectives for Systemic Use Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) Cytochrome P-450 CYP3A7 Inhibitors Cytochrome P-450 CYP3A7 Inhibitors (strength unknown) Cytochrome P-450 Enzyme Inhibitors Enzyme Inhibitors Fluoroquinolones Heterocyclic Compounds, Fused-Ring OAT1/SLC22A6 inhibitors Ophthalmologicals Potential QTc-Prolonging Agents QTc Prolonging Agents Quinolines Quinolone Antimicrobial Quinolones Sensory Organs Topoisomerase II Inhibitors Topoisomerase Inhibitors

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Cross-references: BindingDB: 50045000 ChEBI: 100246 CHEMBL9 ChemSpider: 4380 Drugs Product Database (DPD): 1838 C06687 D00210 PharmGKB: PA450654 PubChem:4539 PubChem:46508634 RxCUI: 7517 Therapeutic Targets Database: DAP000654 Wikipedia: Norfloxacin ZINC: ZINC000000003742