Molecule Details
InChIKeyOFAIGZWCDGNZGT-UHFFFAOYSA-N
Compound NameCaramiphen
Canonical SMILESCCN(CC)CCOC(=O)C1(c2ccccc2)CCCC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL7.64
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB11504
Drug NameCaramiphen
CAS Number77-22-5
Groups experimental vet_approved
ATC Codes nan
DescriptionCaramiphen is a cholinergic antagonist used in Parkinson's disease. Additionally, it is used, in combination with [phenylpropanolamine], as a cough suppressant and nasal decongestant for the symptomatic treatment of seasonal respiratory conditions.

Categories: Cycloparaffins
Cross-references: BindingDB: 73402 ChEBI: 135204 CHEMBL61946 ChemSpider: 6228 RxCUI: 20191 Wikipedia: Caramiphen ZINC: ZINC000001847743
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q99720 SIGMAR1 Homo sapiens Human PF04622 7.7 Ki ChEMBL;BindingDB
P42785 PRCP Homo sapiens Human PF05577 7.6 Ki ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P08172 CHRM2 Muscarinic acetylcholine receptor M2 inhibitor targets
P11229 CHRM1 Muscarinic acetylcholine receptor M1 inhibitor targets