Molecule Details
InChIKeyODNOTLMFNVWFTJ-UHFFFAOYSA-N
Compound Name2-[(6-Pyridin-3-ylisoquinolin-3-yl)amino]ethanol
Canonical SMILESOCCNc1cc2cc(-c3cccnc3)ccc2cn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Homologous
Avg pChEMBL6.76
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.5 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.6 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 7.0 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.9 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.8 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.6 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.5 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.3 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.0 Ki ChEMBL