Molecule Details
InChIKeyOBWGMKKHCLHVIE-UHFFFAOYSA-N
Compound NameFluperlapine
Canonical SMILESCN1CCN(C2=Nc3cc(F)ccc3Cc3ccccc32)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Homologous
Avg pChEMBL7.53
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB20643
Drug NameFluperlapine
CAS Number67121-76-0
Groups experimental
ATC Codes nan
DescriptionFluperlapine is a small molecule drug. Fluperlapine has a monoisotopic molecular weight of 309.16 Da.

Categories: Antipsychotic Agents Central Nervous System Agents Central Nervous System Depressants Heterocyclic Compounds, Fused-Ring Psychotropic Drugs Tranquilizing Agents
Cross-references: BindingDB: 50040241 ChEBI: 5122 CHEMBL63756 C10967 ZINC: ZINC000026247473
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P11229 CHRM1 Homo sapiens Human PF00001 8.1 Ki BindingDB
P08173 CHRM4 Homo sapiens Human PF00001 7.8 Ki BindingDB
P08912 CHRM5 Homo sapiens Human PF00001 7.8 Ki BindingDB
P21917 DRD4 Homo sapiens Human PF00001 7.7 Ki BindingDB
P50406 HTR6 Homo sapiens Human PF00001 7.5 Ki BindingDB
P20309 CHRM3 Homo sapiens Human PF00001 7.4 Ki BindingDB
P28335 HTR2C Homo sapiens Human PF00001 7.2 Ki BindingDB
P08172 CHRM2 Homo sapiens Human PF00001 7.2 Ki BindingDB
P21728 DRD1 Homo sapiens Human PF00001 7.1 Ki BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P34969 HTR7 5-hydroxytryptamine receptor 7 antagonist targets
P50406 HTR6 5-hydroxytryptamine receptor 6 antagonist targets