Molecule Details
| InChIKey | OBNHABKOCPUFDD-YZSQISJMSA-N |
|---|---|
| Compound Name | [(4E)-2-(hydroxymethyl)-4-[[4-[2-(4-methylphenyl)ethynyl]phenyl]methylidene]-5-oxooxolan-2-yl]methyl 1-methylindole-3-carboxylate |
| Canonical SMILES | Cc1ccc(C#Cc2ccc(/C=C3\CC(CO)(COC(=O)c4cn(C)c5ccccc45)OC3=O)cc2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.97 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O95267 | RASGRP1 | Homo sapiens | Human | PF00130 PF00617 PF00618 | 7.4 | Ki | ChEMBL;BindingDB |
| Q02156 | PRKCE | Homo sapiens | Human | PF00130 PF00168 PF00069 PF00433 | 6.9 | Ki | ChEMBL;BindingDB |
| P17252 | PRKCA | Homo sapiens | Human | PF00130 PF00168 PF00069 PF00433 | 6.6 | Ki | ChEMBL;BindingDB |