Molecule Details
InChIKeyOATHVDKMFZZHHN-UHFFFAOYSA-N
Compound NameAntiproliferative agent-30
Canonical SMILESCOc1cc(-c2n[nH]c3ncc(-c4ccc(C)c(NCCO)c4)cc23)cc(OC)c1OC
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL8.0
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
O00238 BMPR1B Homo sapiens Human PF01064 PF07714 PF08515 9.5 Kd ChEMBL
P53779 MAPK10 Homo sapiens Human PF00069 8.6 Kd ChEMBL
Q13163 MAP2K5 Homo sapiens Human PF00564 PF00069 8.2 Kd ChEMBL
O75716 STK16 Homo sapiens Human PF00069 8.0 Kd ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 7.8 Kd ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 7.5 Kd ChEMBL
Q09013 DMPK Homo sapiens Human PF08826 PF00069 7.5 Kd ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 7.5 IC50 ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 7.4 Kd ChEMBL