Molecule Details
InChIKeyOADRBDVURCEKRP-UHFFFAOYSA-N
Compound Name5-bromo-3-phenyl-1H-pyrrolo[2,3-b]pyridine
Canonical SMILESBrc1cnc2[nH]cc(-c3ccccc3)c2c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)44
Pfam Stratification Cross-Family
Avg pChEMBL6.57
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (44)
Target Gene Organism Category Pfam pChEMBL Type Source
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 8.1 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 7.7 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 7.6 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 7.4 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 7.3 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 7.3 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.1 Ki ChEMBL
P16591 FER Homo sapiens Human PF00611 PF07714 PF00017 6.9 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.8 Ki ChEMBL
Q08881 ITK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 6.7 Ki ChEMBL
P15735 PHKG2 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.6 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 6.6 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.5 Ki ChEMBL
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 6.5 Ki ChEMBL
Q13555 CAMK2G Homo sapiens Human PF08332 PF00069 6.5 Ki ChEMBL
Q13557 CAMK2D Homo sapiens Human PF08332 PF00069 6.5 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P27448 MARK3 Homo sapiens Human PF02149 PF00069 PF00627 6.4 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q13554 CAMK2B Homo sapiens Human PF08332 PF00069 6.4 Ki ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 6.4 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.4 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.3 Ki ChEMBL
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.3 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.3 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.2 Ki ChEMBL
P06213 INSR Homo sapiens Human PF00757 PF17870 PF07714 PF01030 6.2 Ki ChEMBL
P07332 FES Homo sapiens Human PF00611 PF07714 PF00017 6.2 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.2 Ki ChEMBL
P51957 NEK4 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9NYL2 MAP3K20 Homo sapiens Human PF07714 PF07647 6.2 Ki ChEMBL
P43405 SYK Homo sapiens Human PF07714 PF00017 6.1 Ki ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q7KZI7 MARK2 Homo sapiens Human PF02149 PF00069 PF00627 6.1 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.0 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.0 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 6.0 Ki ChEMBL