Molecule Details
| InChIKey | NZSGGOJDVRRWTL-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2,5-Diamino-4-(3,4-dichlorophenyl)thieno[2,3-d]pyrimidine-6-carboxamide |
| Canonical SMILES | NC(=O)c1sc2nc(N)nc(-c3ccc(Cl)c(Cl)c3)c2c1N |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.97 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 7.1 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 7.1 | IC50 | ChEMBL |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 7.1 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 7.1 | IC50 | ChEMBL |
| P15056 | BRAF | Homo sapiens | Human | PF00130 PF07714 PF02196 | 6.4 | IC50 | ChEMBL |