Molecule Details
| InChIKey | NYVKAJAAGDOYJD-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-(butylamino)-4-[(4-hydroxycyclohexyl)amino]-N-[[2-(trifluoromethyl)phenyl]methyl]pyrimidine-5-carboxamide |
| Canonical SMILES | CCCCNc1ncc(C(=O)NCc2ccccc2C(F)(F)F)c(NC2CCC(O)CC2)n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.76 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q12866 | MERTK | Homo sapiens | Human | PF00041 PF00047 PF13927 PF07714 | 7.5 | IC50 | ChEMBL;BindingDB |
| P36888 | FLT3 | Homo sapiens | Human | PF00047 PF07714 | 6.4 | IC50 | ChEMBL;BindingDB |
| Q14393 | GAS6 | Homo sapiens | Human | PF12662 PF07645 PF00594 PF12661 PF00054 PF02210 | 6.4 | IC50 | ChEMBL;BindingDB |