Molecule Details
| InChIKey | NYKCGQQJNVPOLU-ONTIZHBOSA-N |
|---|---|
| Compound Name | Spiradoline |
| Canonical SMILES | CN(C(=O)Cc1ccc(Cl)c(Cl)c1)[C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.07 |
| Source | BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB12704 |
|---|---|
| Drug Name | Spiradoline |
| CAS Number | 87151-85-7 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Spiradoline has been investigated for the basic science of Bipolar Depression. |
Categories: Analgesics Antiarrhythmic agents Cardiovascular Agents Central Nervous System Agents Diuretics Natriuretic Agents Peripheral Nervous System Agents Receptors, Opioid, kappa, agonists Sensory System Agents
Cross-references: BindingDB: 83436 CHEMBL70586 ChemSpider: 50257 PubChem:55652 PubChem:347828902 Wikipedia: Spiradoline ZINC: ZINC000002530707
Target Activities (3)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P41145 | OPRK1 | Kappa-type opioid receptor | agonist | targets |