Molecule Details
| InChIKey | NWAWSQQMTQQBGL-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-ethoxy-N-(6-hydroxyhexyl)-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-5-yl)benzenesulfonamide |
| Canonical SMILES | CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)NCCCCCCO)ccc3OCC)nc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.64 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O76074 | PDE5A | Homo sapiens | Human | PF01590 PF00233 | 8.8 | IC50 | ChEMBL;BindingDB |
| P51160 | PDE6C | Homo sapiens | Human | PF01590 PF00233 | 8.3 | IC50 | ChEMBL;BindingDB |
| P54750 | PDE1A | Homo sapiens | Human | PF00233 PF08499 | 7.2 | IC50 | ChEMBL;BindingDB |
| O00408 | PDE2A | Homo sapiens | Human | PF01590 PF00233 | 6.2 | IC50 | ChEMBL;BindingDB |