Molecule Details
| InChIKey | NVVPMZUGELHVMH-UHFFFAOYSA-N |
|---|---|
| Canonical SMILES | CCc1cc(C(N)=O)ccc1-n1nc(C(C)C)c2c(-n3cnc(-c4cnn(C)c4)c3)ccnc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.42 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB14876 |
|---|---|
| Drug Name | Pimitespib |
| CAS Number | 1260533-36-5 |
| Groups | investigational |
| ATC Codes | nan |
| Description | TAS-116 is under investigation in clinical trial NCT02965885 (A Study of TAS-116 in Patients With Solid Tumors). |
Categories: Acids, Carbocyclic Amides Benzene Derivatives Benzoates
Cross-references: BindingDB: 126083 CHEMBL3661115 ChemSpider: 58796458 PDB: A1BPC ZINC: ZINC000169703510
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P08238 | HSP90AB1 | Heat shock protein HSP 90-beta | inhibitor | targets |