Molecule Details
InChIKeyNTVFVNYEAMJGDF-HXUWFJFHSA-N
Compound Name4-[[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-3-(2-hydroxyethoxy)-N-propylbenzamide
Canonical SMILESCCCNC(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)c(OCCO)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL6.67
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P53350 PLK1 Homo sapiens Human PF00069 PF00659 7.4 IC50 ChEMBL;BindingDB
Q9H4B4 PLK3 Homo sapiens Human PF00069 PF00659 6.4 IC50 ChEMBL;BindingDB
Q9NYY3 PLK2 Homo sapiens Human PF00069 PF00659 6.2 IC50 ChEMBL;BindingDB