N-[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]-2-[[4-(1,2,4-triazol-1-yl)phenyl]methyl]-1,3-thiazole-4-carboxamide

InChIKey	`NTVCUWWTUPIBEG-HNNXBMFYSA-N`
Compound Name	N-[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]-2-[[4-(1,2,4-triazol-1-yl)phenyl]methyl]-1,3-thiazole-4-carboxamide
Canonical SMILES	`N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2ccc(-n3cncn3)cc2)n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	6.97
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q12884	FAP	Homo sapiens	Human	PF00930 PF00326	7.5	IC50	ChEMBL
P48147	PREP	Homo sapiens	Human	PF00326 PF02897	6.4	IC50	ChEMBL;BindingDB